Product Description
Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The mo… More >>
Product Description
In recent years remarkable progress has been accomplished with respect to our knowledge about bacterial protein toxins. This refers especially to structural aspects of protein toxins but also holds true for genetics, molecular biology and biochemical mechanisms underlying the action of toxins. This volume covers the very current and exciting aspects of up-to-date bacterial toxicology and comprehensively reviews the most important bacterial protein toxins such as the… More >>
Product Description
This is a survey of well characterized and recently discovered bacterial protein toxins. Leading investigators of the respective toxins review the various molecular mechanisms of action, ranging from toxin-induced ADP-ribosylation up to membrane perforation by pore-forming toxins. Thy also describe the consequences on host physiology before focusing on potential applications as cell biological and pharmacological tools for research and medical applications. Detailed… More >>
Product Description
Detailing the diverse ways bacterial toxins subvert cellular metabolism and signalling, this state-of-the-art reference describes the structure and function of bacterial toxins and presents a comprehensive review of virulence factors — providing the latest information concerning cell physiology and biochemistry, as well as new toxin tools for experimental studies and clinical therapy…. More >>