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The true extent of prokaryote diversity, encompassing the spectrum of variability among bacteria, remains unknown. Current research efforts focus on understanding why prokaryote diversification occurs, its underlying mechanisms, and its likely impact. The dynamic nature of the prokaryotic world, and continuing advances in the technological tools available make this an important area and hence this book will appeal to a wide variety of microbiologists. Its coverage r… More >>
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This is the first volume to bring together the studies on the differences and profound similarities in the molecular mechanism of virulence between bacteria pathogenic for humans, animals and plants. The volume contains the following sections: 1. Host cell recognition and binding; 2. Pathogen ingression and invasive mechanism; 3. Enzymes, toxins and other pathogenic factors; 4. Regulation of virulence genes and signal transduction; 5. Pathogen of host-defense … More >>
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Microbial responses to acidic and alkaline pH are important in many areas of bacteriology. For example, the mechanisms of resistance to acidic pH are important in the understanding of the passage of human pathogens through the acid of the stomach; and an understanding of microbial degradation of alkaline industrial waste is important for the environment.
Bringing together contributions from an international and interdisciplinary group of experts worki… More >>
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Escherichia coli: Virulence Mechanisms of a Versatile Pathogen is a unique, comprehensive analysis of the biology and molecular mechanisms that enable this ubiquitous organism to thrive. Leading investigators in the field discuss the molecular basis of E. coli pathogenesis followed by chapters on genomics and evolution. Detailed descriptions of distinct strains reveal the molecular pathogenesis of each and the causes of intestinal and extra-intestinal infecti… More >>
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This comprehensive compilation, written by an authoritative team of international contributors, surveys the role E. coli plays in health and disease. First, the diseases in humans and animals attributable to E. coli are described in general terms, including a discussion of the part it plays in the normal flora of humans and animals. The next section is devoted to each of the recognized virulence factors and mechanisms, including capsules, adhesins, hemolysins, endot… More >>
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This book addresses the unique features of four microorganisms that constitute the top bioterror threat agents: Bacillus anthracis; Yersinia pestis, Francisella tularensis and Orthopoxviruses. Side-by-side updated information about their pathogenisis, virulence and epidemiology is provided in a single volume, allowing for evaluation of common features as well as common strategies for defense. Classical microbiological as well as genomic, proteomic & transcriptom… More >>
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An emerging theme in molecular and cellular microbiology has been the ability of many pathogens to usurp the host cell and eventually colonize the host. This interaction between bacteria and host is not unidirectional – both pathogens and host cells engage in a signalling cross-talk. Research focused on this cross-talk and discussed in this volume, reveals not only novel aspects of bacterial pathogenesis, but also key information about epithelial biology with broade… More >>
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The field of endotoxin research is constantly expanding. Modern technology and tools are now providing so much data that the importance of identifying the data which are physiologically relevant and which will lead to the effective treatment of the wide variety of clinical disorders in which endotoxin may play an important role has assumed even greater significance than before. This book, the second volume in the Endotoxin Research series, presents all the papers fo… More >>